ATRX: Put Me on Repeat

ATRX: Put Me on Repeat

Mutations in the chromatin-remodeling protein ATRX cause alpha thalassaemia and mental retardation, but the severity of the disorder is independent of the specific mutation. In this issue of Cell, Law et al. (2010) demonstrate that ATRX alters gene expression by binding to G-rich tandem repeats, and the degree of transcriptional silencing caused by ATRX mutations correlates with the number of r...

Put Me in the Sky1

" I thought that I was going to be a doctor, and I majored in science and later in mathematics. But when I got out of college, I decided to study art, " divulged Romare Bearden in a 1968 oral history interview. In New York, " I went to study with George Grosz at the Art Students League. " The German-born artist guided Bearden's understanding of draftsmanship and classical technique, introducing...

Doctor, Did You Put a Mesh on Me That Is No Longer Recommended?

Repeat after me: Replication in clinical neuroimaging is critical

NeuroImage: Clinical is a journal that specifically deals with novel insights relating to the use of neuroimaging to improve our understanding, diagnosis and treatment of brain-related disorders. The numerous papers already submitted have confirmed that the importance of this enterprise is recognised by the wider clinical community. We hope that the journal will continue to growand come tobe a ...

Repeat After Me: Dance Program Evaluation for the Friendship Circle

Approximately 1 in 6 children in the United States are diagnosed with one or more developmental disabilities or delays (Boyle et al., 2011). Although the number of therapeutic approaches for children with developmental disabilities has increased, no single treatment or combination of treatments is effective in relieving symptoms for all individuals (Scharoun, Reinders, Bryden & Fletcher, 2014)....